When you have reached a high plateau, ascending still higher gets more difficult. Yet glorious opportunities remain. We can apply our existing physical knowledge to make ingenious and useful things, like computers that leverage the richness of the quantum world to store and manipulate information more effectively. And important theoretical questions remain to be answered. For instance, we still haven't got a clear picture of what most of the universe, measured by mass, is made of.
— The Wall Street Journal - Have We Come To the End of Physics?
by Frank Wilczek